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Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.

Peroxynitrite is a potent oxidizing and nitrating species formed in a diffusion-limited reaction between nitrogen monoxide and superoxide. It induces apoptosis through unknown mechanisms and is believed to interfere with receptor tyrosine kinase signalling through nitration of tyrosine residues. One...

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Sonraí Bibleagrafaíochta
Main Authors: Klotz, L O, Schieke, S M, Sies, H, Holbrook, N J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2000
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221450/
https://ncbi.nlm.nih.gov/pubmed/11062076
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