Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway

Pulmonary fibrosis is characterized by lung fibroblast proliferation and collagen secretion. In lipopolysaccharide (LPS)-induced acute lung injury (ALI), aberrant proliferation of lung fibroblasts is initiated in early disease stages, but the underlying mechanism remains unknown. In this study, we k...

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Detalhes bibliográficos
Main Authors: He, Zhengyu, Gao, Yuan, Deng, Yuxiao, Li, Wen, Chen, Yongming, Xing, Shunpeng, Zhao, Xianyuan, Ding, Jia, Wang, Xiangrui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338545/
https://ncbi.nlm.nih.gov/pubmed/22563417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035926
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