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Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth

BACKGROUND: The outgrowth of new vessels – angiogenesis – in the tumour mass is considered to be a limiting factor of tumour growth. To inhibit the matrix lysis that is part of the tumour angiogenesis, we employed the chimeric protein mhATF-BPTI, composed of the receptor binding part of the urokinas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lefesvre, Pierre, Attema, Joline, van Bekkum, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122087/
https://ncbi.nlm.nih.gov/pubmed/12147175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-2-17
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