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Pharmacogenetic heterogeneity of transgene expression in muscle and tumours

BACKGROUND: Recombinant adenoviruses are employed to deliver a therapeutic transgene in the liver, muscle or tumour tissue. However, to rationalise this delivery approach, the factors of variation between individuals need to be identified. It is assumed that differences between inbred strains of lab...

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Detalhes bibliográficos
Main Authors: Lefesvre, Pierre, Attema, Joline, van Bekkum, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC194725/
https://ncbi.nlm.nih.gov/pubmed/12943556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-3-11
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