Interferon-gamma-dependent stimulation of human involucrin gene expression: STAT1 (signal transduction and activators of transcription 1) protein activates involucrin promoter activity.

Involucrin is one of the precursor proteins of the cornified cell envelope of keratinocytes, and is expressed during the later stages of keratinocyte differentiation. Interferon-gamma (IFN-gamma), a pleiotropic cytokine with anti-proliferative and immunomodulatory activities, is also a potent induce...

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Detalhes bibliográficos
Main Authors: Takahashi, H, Asano, K, Nakamura, S, Ishida-Yamamoto, A, Iizuka, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220701/
https://ncbi.nlm.nih.gov/pubmed/10585866
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