Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIalpha gene promoter.

DNA topoisomerase IIalpha (topo IIalpha) is an essential nuclear enzyme required for chromosome segregation during mitosis. Consistent with its critical role in cell division is the fact that the expression of the gene for topo IIalpha is strongly regulated by the proliferation state of cells. Using...

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Bibliografske podrobnosti
Main Authors: Yoon, J H, Kim, J K, Rha, G B, Oh, M, Park, S H, Seong, R H, Hong, S H, Park, S D
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220652/
https://ncbi.nlm.nih.gov/pubmed/10567217
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