Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIalpha gene promoter.

DNA topoisomerase IIalpha (topo IIalpha) is an essential nuclear enzyme required for chromosome segregation during mitosis. Consistent with its critical role in cell division is the fact that the expression of the gene for topo IIalpha is strongly regulated by the proliferation state of cells. Using...

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Main Authors: Yoon, J H, Kim, J K, Rha, G B, Oh, M, Park, S H, Seong, R H, Hong, S H, Park, S D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220652/
https://ncbi.nlm.nih.gov/pubmed/10567217
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