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Expression of topoisomerase IIalpha is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer.

The role of molecular markers predicting the response to cytotoxic chemotherapy is not established. A potential predictive factor, topoisomerase IIalpha, is a target for certain cytotoxic drugs, and its concentration has been shown to correlate with chemosensitivity in vitro. We evaluated expression...

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Библиографические подробности
Главные авторы: Järvinen, T. A., Kononen, J., Pelto-Huikko, M., Isola, J.
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861630/
https://ncbi.nlm.nih.gov/pubmed/8669491
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