Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo.

3-phosphoinositide-dependent protein kinase-1 (PDK1) expressed in unstimulated 293 cells was phosphorylated at Ser-25, Ser-241, Ser-393, Ser-396 and Ser-410 and the level of phosphorylation of each site was unaffected by stimulation with insulin-like growth factor-1. Mutation of Ser-241 to Ala aboli...

Full description

Saved in:
Bibliographic Details
Main Authors: Casamayor, A, Morrice, N A, Alessi, D R
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220463/
https://ncbi.nlm.nih.gov/pubmed/10455013
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items