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Thioredoxin reductase is the major selenoprotein expressed in human umbilical-vein endothelial cells and is regulated by protein kinase C.

Damage to the endothelium by reactive oxygen species favours atherogenesis. Such damage can be prevented by selenium, which is thought to exert its actions through the expression of selenoproteins. The family of glutathione peroxidases (GPXs) may have antioxidant roles in the endothelium but other i...

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Detalhes bibliográficos
Main Authors: Anema, S M, Walker, S W, Howie, A F, Arthur, J R, Nicol, F, Beckett, G J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220443/
https://ncbi.nlm.nih.gov/pubmed/10432307
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