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Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo.

Anti-sense oligodeoxynucleotides (ODNs) hold great promise for correcting the biosynthesis of clinically relevant proteins. The potential of ODNs for modulating liver-specific genes might be increased by preventing untimely elimination and by improving the local bioavailability of ODNs in the target...

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Main Authors: Biessen, E A, Vietsch, H, Rump, E T, Fluiter, K, Kuiper, J, Bijsterbosch, M K, van Berkel, T J
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220312/
https://ncbi.nlm.nih.gov/pubmed/10359665
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