Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.

Nitric oxide (NO) synthases (NOSs), which catalyse the oxidation of L-arginine to L-citrulline and an oxide of nitrogen, possibly NO or nitroxyl (NO-), are subject to autoinhibition by a mechanism that has yet to be fully elucidated. In the present study we investigated the actions of NO and other N...

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Hauptverfasser: Kotsonis, P, Frey, A, Fröhlich, L G, Hofmann, H, Reif, A, Wink, D A, Feelisch, M, Schmidt, H H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220307/
https://ncbi.nlm.nih.gov/pubmed/10359660
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