Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans.

A series of benzofuran derivatives have been identified as inhibitors of fibril formation in the beta-amyloid peptide. The activity of these compounds has been assessed by a novel fibril-formation-specific immunoassay and for their effects on the production of a biologically active fibril product. T...

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Autores principales: Howlett, D R, Perry, A E, Godfrey, F, Swatton, J E, Jennings, K H, Spitzfaden, C, Wadsworth, H, Wood, S J, Markwell, R E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220247/
https://ncbi.nlm.nih.gov/pubmed/10229684
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