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Assembling amyloid fibrils from designed structures containing a significant amyloid beta-peptide fragment.
The amyloid plaque, consisting of amyloid beta-peptide (Abeta) fibrils surrounded by dystrophic neurites, is an invariable feature of Alzheimer's disease. The determination of the molecular structure of Abeta fibrils is a significant goal that may lead to the structure-based design of effective...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1222771/ https://ncbi.nlm.nih.gov/pubmed/12023906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020229 |
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