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Amyloid precursor protein metabolism in fibroblasts from individuals with one, two or three copies of the amyloid precursor protein (APP) gene.

Protein kinase C (PKC)-activated modulation of amyloid precursor protein (APP) metabolism has been investigated in natural models of altered APP expression due to the presence of one, two or three copies of the APP gene. We show that levels of APP present in human skin fibroblasts strongly influence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Racchi, M, Johnston, J A, Flood, F M, Cowburn, R F, Govoni, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220116/
https://ncbi.nlm.nih.gov/pubmed/10051452
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