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Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane.
The C2 domain is a conserved protein module present in various signal-transducing proteins. To investigate the function of the C2 domain of protein kinase Calpha (PKCalpha), we have generated a recombinant glutathione S-transferase-fused C2 domain from rat PKCalpha, PKC-C2. We found that PKC-C2 bind...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1220004/ https://ncbi.nlm.nih.gov/pubmed/9895296 |
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