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Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase.

The nitric oxide synthases are dimeric enzymes in which the intersubunit contacts are formed by the P-450-haem-containing, tetrahydrobiopterin-dependent oxygenase domain. The dimerization of the neuronal isoenzyme was shown previously to be triggered by Fe-protoporphyrin IX (haemin). We report for t...

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Detalhes bibliográficos
Main Authors: Hemmens, B, Gorren, A C, Schmidt, K, Werner, E R, Mayer, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219487/
https://ncbi.nlm.nih.gov/pubmed/9601061
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