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Effects of pH on the structure and function of neuronal nitric oxide synthase.

We investigated how pH affects rat brain neuronal nitric oxide synthase (nNOS) with regard to spin-state equilibrium and the thiolate ligand bond of the haem group, catalytic activity, and monomerleft and right arrow dimer equilibrium. At neutral pH, nNOS containing 1 equiv. of (6R)-5,6,7,8-tetrahyd...

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Main Authors: Gorren, A C, Schrammel, A, Schmidt, K, Mayer, B
格式: Artigo
語言:Inglês
出版: 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219420/
https://ncbi.nlm.nih.gov/pubmed/9560307
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