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Selective Irreversible Inhibition of Neuronal and Inducible Nitric-oxide Synthase in the Combined Presence of Hydrogen Sulfide and Nitric Oxide
Citrulline formation by both human neuronal nitric-oxide synthase (nNOS) and mouse macrophage inducible NOS was inhibited by the hydrogen sulfide (H(2)S) donor Na(2)S with IC(50) values of ∼2.4·10(−5) and ∼7.9·10(−5) m, respectively, whereas human endothelial NOS was hardly affected at all. Inhibiti...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599001/ https://ncbi.nlm.nih.gov/pubmed/26296888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660316 |
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