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The plasma membrane of Leishmania donovani promastigotes is the main target for CA(1-8)M(1-18), a synthetic cecropin A-melittin hybrid peptide.

Reports on the lethal activity of animal antibiotic peptides have largely focused on bacterial rather than eukaryotic targets. In these, involvement of internal organelles as well as mechanisms different from those of prokaryotic cells have been described. CA(1-8)M(1-18) is a synthetic cecropin A-me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Díaz-Achirica, P, Ubach, J, Guinea, A, Andreu, D, Rivas, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219160/
https://ncbi.nlm.nih.gov/pubmed/9461543
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