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Interleukin-6 is necessary, but not sufficient, for induction of the humanC-reactive protein gene in vivo.

We have investigated the involvement of interleukin-6 (IL-6) in the induction of the gene encoding the acute-phase protein human C-reactive protein (hCRP). In transgenic mice the hCRP gene can be induced by lipopolysaccharide (LPS), but not by IL-6. In contrast, hCRP was inducible by IL-6 in primary...

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Hlavní autoři: Weinhold, B, Bader, A, Poli, V, Rüther, U
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218603/
https://ncbi.nlm.nih.gov/pubmed/9271080
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