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Interleukin-6-dependent and -independent regulation of the human C-reactive protein gene.

We have investigated the function of different mediators of the regulation of the human C-reactive protein (hCRP) gene in transgenic mice. hCRP was induced by lipopolysaccharide and wounding in interleukin-6 (IL-6) +/+ mice, but not in IL-6 -/- mice. This finding suggested that IL-6 is necessary for...

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Detalhes bibliográficos
Main Authors: Weinhold, B, Rüther, U
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218811/
https://ncbi.nlm.nih.gov/pubmed/9359411
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