Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids.

Ubiquitin is a 76-amino acid protein involved in the targeting for destruction of proteins in the cell. The protein can readily be synthesized chemically affording an extra dimension to studies of protein stability. Ubiquitin with various modifications to the hydrophobic core has been synthesized. I...

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Main Authors: Love, S G, Muir, T W, Ramage, R, Shaw, K T, Alexeev, D, Sawyer, L, Kelly, S M, Price, N C, Arnold, J E, Mee, M P, Mayer, R J
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218376/
https://ncbi.nlm.nih.gov/pubmed/9169606
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