Synthetic, structural and biological studies of the ubiquitin system: chemically synthesized and native ubiquitin fold into identical three-dimensional structures.

The solid-phase chemical synthesis of ubiquitin produced a molecule with physicochemical properties similar to those of the natural protein. We have grown crystals of this synthetic ubiquitin and performed an X-ray analysis at 1.8 A resolution in order to compare the synthetic protein with the known...

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Detalhes bibliográficos
Main Authors: Alexeev, D, Bury, S M, Turner, M A, Ogunjobi, O M, Muir, T W, Ramage, R, Sawyer, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138035/
https://ncbi.nlm.nih.gov/pubmed/8166634
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