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The folding mechanism of larger model proteins: role of native structure.

The folding mechanism of a 125-bead heteropolymer model for proteins is investigated with Monte Carlo simulations on a cubic lattice. Sequences that do and do not fold in a reasonable time are compared. The overall folding behavior is found to be more complex than that of models for smaller proteins...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Dinner, A R, Sali, A, Karplus, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8356
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