Allosteric modulation of the activity of thrombin.

Substrates containing a P3 aspartic residue are in general cleaved poorly by thrombin. This may be partly due to an unfavourable interaction between the P3 aspartate and Glu192 in the active site of thrombin. In Protein C activation and perhaps also thrombin receptor cleavage, binding of ligands at...

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Detaylı Bibliyografya
Asıl Yazarlar: Duffy, E J, Angliker, H, Le Bonniec, B F, Stone, S R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218077/
https://ncbi.nlm.nih.gov/pubmed/9020867
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