טוען...

Contribution of interactions with the core domain of hirudin to the stability of its complex with thrombin.

The importance of interactions with residues 15-21 in the core domain of hirudin for the formation of the complex with thrombin has been investigated by site-directed mutagenesis. Contacts made by Leu-15 were found to be particularly important; replacement of this residue by alanine led to a decreas...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Betz, A, Hopkins, P C, Le Bonniec, B F, Stone, S R
פורמט: Artigo
שפה:Inglês
יצא לאור: 1994
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137969/
https://ncbi.nlm.nih.gov/pubmed/8135762
תגים: הוספת תג
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