Heparin enhances the catalytic activity of des-ETW-thrombin.

The thrombin mutant, des-ETW-thrombin, lacking Glu(146), Thr(147), and Trp(148) within a unique insertion loop located at the extreme end of the primary specificity pocket, has been shown previously to exhibit reduced catalytic activity with respect to macromolecular and synthetic thrombin substrate...

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Detalhes bibliográficos
Main Authors: Goodwin, C A, Deadman, J J, Le Bonniec, B F, Elgendy, S, Kakkar, V V, Scully, M F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217199/
https://ncbi.nlm.nih.gov/pubmed/8670135
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