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A type 2A phosphatase-sensitive phosphorylation site controls modal gating of L-type Ca2+ channels in human vascular smooth-muscle cells.
The patch-clamp technique was employed to investigate phosphorylation/dephosphorylation-dependent modulation of L-type Ca2+ channels in smooth-muscle cells isolated from human umbilical vein. Okadaic acid, an inhibitor of phosphoprotein phosphatases type 1 (PP1) and 2A (PP2A), increased the probabil...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
1996
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1217650/ https://ncbi.nlm.nih.gov/pubmed/8809040 |
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