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Intracellular Ca(2+) Inhibits Smooth Muscle L-Type Ca(2+) Channels by Activation of Protein Phosphatase Type 2B and by Direct Interaction with the Channel

Modulation of L-type Ca(2+) channels by tonic elevation of cytoplasmic Ca(2+) was investigated in intact cells and inside-out patches from human umbilical vein smooth muscle. Ba(2+) was used as charge carrier, and run down of Ca(2+) channel activity in inside-out patches was prevented with calpastat...

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Detalhes bibliográficos
Main Authors: Schuhmann, Klaus, Romanin, Christoph, Baumgartner, Werner, Groschner, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229392/
https://ncbi.nlm.nih.gov/pubmed/9348323
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