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Inhibition of protein synthesis in frog (Xenopus laevis) egg extracts by an antibody against phosphatidylinositol 4,5-bisphosphate.

The antibody kt10, which is directed against the phospholipid PtdIns(4,5)P2, inhibits protein synthesis when added to cytosolic extracts prepared from frog eggs. Addition of stable analogues of diacylglycerol and Ins(1,4,5)P3 failed to rescue the inhibition of translation, suggesting that the effect...

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Sonraí Bibleagrafaíochta
Main Authors: Keating, T J, Fukami, K, Robinson, K R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217534/
https://ncbi.nlm.nih.gov/pubmed/8760344
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