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Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.

Disruption of the murine mdr2 gene leads to the complete absence of biliary phospholipids. We tested the hypothesis that the increase in biliary phospholipid output induced by fibrates is mediated via induction of the hepatic mdr2 gene and its encoded product, the P-glucoprotein canalicular flippase...

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Detalhes bibliográficos
Main Authors: Chianale, J, Vollrath, V, Wielandt, A M, Amigo, L, Rigotti, A, Nervi, F, Gonzalez, S, Andrade, L, Pizarro, M, Accatino, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217124/
https://ncbi.nlm.nih.gov/pubmed/8615769
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