Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.

Disruption of the murine mdr2 gene leads to the complete absence of biliary phospholipids. We tested the hypothesis that the increase in biliary phospholipid output induced by fibrates is mediated via induction of the hepatic mdr2 gene and its encoded product, the P-glucoprotein canalicular flippase...

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Hlavní autoři: Chianale, J, Vollrath, V, Wielandt, A M, Amigo, L, Rigotti, A, Nervi, F, Gonzalez, S, Andrade, L, Pizarro, M, Accatino, L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217124/
https://ncbi.nlm.nih.gov/pubmed/8615769
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