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Selection of hammerhead ribozymes for optimum cleavage of interleukin 6 mRNA.

Four GUC triplets in the coding region of the MRNA of interleukin 6 (IL-6) were examined for their suitabilty to serve as a target for hammerhead ribozome-mediated cleavage. This selection procedure was performed with the intention to downregulate IL-6 production as a potential treatment of those di...

詳細記述

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書誌詳細
主要な著者: Hendrix, C, Anné, J, Joris, B, Van Aerschot, A, Herdewijn, P
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217097/
https://ncbi.nlm.nih.gov/pubmed/8670082
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