Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.

Crigler-Najjar (CN) disease is an inherited disorder of bilirubin metabolism. The disease is caused by a deficiency of the hepatic enzyme bilirubin UDP-glucuronosyltransferase (B-UGT). Patients with CN disease have high serum levels of the toxic compound, unconjugated bilirubin. The only defect in b...

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Main Authors: Seppen, J, Tada, K, Hellwig, S, Bakker, C T, Prasad, V R, Roy Chowdhury, N, Roy Chowdhury, J, Bosma, P J, Oude Elferink, R P
格式: Artigo
語言:Inglês
出版: 1996
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217075/
https://ncbi.nlm.nih.gov/pubmed/8670060
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