Production and characterization of amplified tumor-derived cRNA libraries to be used as vaccines against metastatic melanomas

BACKGROUND: Anti-tumor vaccines targeting the entire tumor antigen repertoire represent an attractive immunotherapeutic approach. In the context of a phase I/II clinical trial, we vaccinated metastatic melanoma patients with autologous amplified tumor mRNA. In order to provide the large quantities o...

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Detalhes bibliográficos
Main Authors: Carralot, Jean-Philippe, Weide, Benjamin, Schoor, Oliver, Probst, Jochen, Scheel, Birgit, Teufel, Regina, Hoerr, Ingmar, Garbe, Claus, Rammensee, Hans-Georg, Pascolo, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1215502/
https://ncbi.nlm.nih.gov/pubmed/16115316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-3-6
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