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Characterization of the ribonuclease activity on the skin surface

The rapid degradation of ribonucleic acids (RNA) by ubiquitous ribonucleases limits the efficacy of new therapies based on RNA molecules. Therefore, our aim was to characterize the natural ribonuclease activities on the skin and in blood plasma i.e. at sites where many drugs in development are appli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Probst, Jochen, Brechtel, Sonja, Scheel, Birgit, Hoerr, Ingmar, Jung, Günther, Rammensee, Hans-Georg, Pascolo, Steve
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524753/
https://ncbi.nlm.nih.gov/pubmed/16732888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-4-4
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