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Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo

During asymmetric cell division, the membrane-associated Numb protein localizes to a crescent in the mitotic progenitor and is segregated predominantly to one of the two daughter cells. We have identified a putative serine/threonine kinase, Numb-associated kinase (Nak), which interacts physically wi...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Chien, Cheng-ting, Wang, Shuwen, Rothenberg, Michael, Jan, Lily Y., Jan, Yuh Nung
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.598
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