MYC Abrogates p53-Mediated Cell Cycle Arrest in N-(Phosphonacetyl)-l-Aspartate-Treated Cells, Permitting CAD Gene Amplification
Genomic instability, including the ability to undergo gene amplification, is a hallmark of neoplastic cells. Similar to normal cells, “nonpermissive” REF52 cells do not develop resistance to N-(phosphonacetyl)-l-aspartate (PALA), an inhibitor of the synthesis of pyrimidine nucleotides, through ampli...
Zapisane w:
| Wydane w: | Mol Cell Biol |
|---|---|
| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1998
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.536 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
