Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300

The human T-cell leukemia virus type 1 Tax protein transforms human T lymphocytes, which can lead to the development of adult T-cell leukemia. Tax transformation is related to its ability to activate gene expression via the ATF/CREB and the NF-κB pathways. Transcriptional activation of these pathway...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Bex, Françoise, Yin, Min-Jean, Burny, Arsène, Gaynor, Richard B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1998
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2392
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