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Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300

The human T-cell leukemia virus type 1 Tax protein transforms human T lymphocytes, which can lead to the development of adult T-cell leukemia. Tax transformation is related to its ability to activate gene expression via the ATF/CREB and the NF-κB pathways. Transcriptional activation of these pathway...

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Udgivet i:Mol Cell Biol
Principais autores: Bex, Françoise, Yin, Min-Jean, Burny, Arsène, Gaynor, Richard B.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2392
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