QR kód

Autophosphorylation in the Activation Loop Is Required for Full Kinase Activity In Vivo of Human and Yeast Eukaryotic Initiation Factor 2α Kinases PKR and GCN2

The human double-stranded RNA-dependent protein kinase (PKR) is an important component of the interferon response to virus infection. The activation of PKR is accompanied by autophosphorylation at multiple sites, including one in the N-terminal regulatory region (Thr-258) that is required for full k...

Celý popis

Uloženo v:
Vydáno v:Mol Cell Biol
Hlavní autoři: Romano, Patrick R., Garcia-Barrio, Minerva T., Zhang, Xiaolong, Wang, Qizhi, Taylor, Deborah R., Zhang, Fan, Herring, Christopher, Mathews, Michael B., Qin, Jun, Hinnebusch, Alan G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1998
Témata:
Gene Expression
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2282
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky