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Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells

The Rel/NF-κB family of transcription factors is sequestered in the cytoplasm of most mammalian cells by inhibitor proteins belonging to the IκB family. Degradation of IκB by a phosphorylation-dependent ubiquitin-proteasome (inducible) pathway is believed to allow nuclear transport of active Rel/NF-...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Miyamoto, Shigeki, Seufzer, Bradley J., Shumway, Stuart D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.19
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