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Protein Serine/Threonine Phosphatase Ptc2p Negatively Regulates the Unfolded-Protein Response by Dephosphorylating Ire1p Kinase

Cells respond to the accumulation of unfolded proteins in the endoplasmic reticulum (ER) by increasing the transcription of the genes encoding ER-resident chaperone proteins. Ire1p is a transmembrane protein kinase that transmits the signal from unfolded proteins in the lumen of the ER by a mechanis...

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Bibliografski detalji
Glavni autori: Welihinda, Ajith A., Tirasophon, Witoon, Green, Sarah R., Kaufman, Randal J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC121426/
https://ncbi.nlm.nih.gov/pubmed/9528768
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