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Differential Restriction of Human Immunodeficiency Virus Type 2 and Simian Immunodeficiency Virus SIVmac by TRIM5α Alleles

Primate lentiviruses have narrow host ranges, due in part to their sensitivities to mammalian intracellular antiviral factors such as APOBEC3G and TRIM5α. Despite the protection provided by this innate immune system, retroviruses are able to transfer between species where they can cause disease. Thi...

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Autores principales: Ylinen, Laura M. J., Keckesova, Zuzana, Wilson, Sam J., Ranasinghe, Srinika, Towers, Greg J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212619/
https://ncbi.nlm.nih.gov/pubmed/16140735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11580-11587.2005
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