Molecular Basis of Replication of Duck H5N1 Influenza Viruses in a Mammalian Mouse Model

We recently analyzed a series of H5N1 viruses isolated from healthy ducks in southern China since 1999 and found that these viruses had progressively acquired the ability to replicate and cause disease in mice. In the present study, we explored the genetic basis of this change in host range by compa...

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Bibliographische Detailangaben
Hauptverfasser: Li, Zejun, Chen, Hualan, Jiao, Peirong, Deng, Guohua, Tian, Guobin, Li, Yanbing, Hoffmann, Erich, Webster, Robert G., Matsuoka, Yumiko, Yu, Kangzhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212590/
https://ncbi.nlm.nih.gov/pubmed/16140781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.12058-12064.2005
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