Minimal T-Cell-Stimulatory Sequences and Spectrum of HLA Restriction of Immunodominant CD4(+) T-Cell Epitopes within Hepatitis C Virus NS3 and NS4 Proteins

The hepatitis C virus (HCV)-specific CD4(+) T-cell response against nonstructural proteins is strongly associated with successful viral clearance during acute hepatitis C. To further develop these observations into peptide-based vaccines and clinical immunomonitoring tools like HLA class II tetramer...

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Detalhes bibliográficos
Main Authors: Gerlach, J. T., Ulsenheimer, A., Grüner, N. H., Jung, M.-C., Schraut, W., Schirren, C.-A., Heeg, M., Scholz, S., Witter, K., Zahn, R., Vogler, A., Zachoval, R., Pape, G. R., Diepolder, H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211510/
https://ncbi.nlm.nih.gov/pubmed/16160170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12425-12433.2005
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