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Minimal T-Cell-Stimulatory Sequences and Spectrum of HLA Restriction of Immunodominant CD4(+) T-Cell Epitopes within Hepatitis C Virus NS3 and NS4 Proteins
The hepatitis C virus (HCV)-specific CD4(+) T-cell response against nonstructural proteins is strongly associated with successful viral clearance during acute hepatitis C. To further develop these observations into peptide-based vaccines and clinical immunomonitoring tools like HLA class II tetramer...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1211510/ https://ncbi.nlm.nih.gov/pubmed/16160170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12425-12433.2005 |
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