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Sulindac metabolites inhibit epidermal growth factor receptor activation and expression
BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a decreased mortality from colorectal cancer (CRC). NSAIDs induce apoptotic cell death in colon cancer cells in vitro and inhibit growth of neoplastic colonic mucosa in vivo however, the biochemical mechanism...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1208922/ https://ncbi.nlm.nih.gov/pubmed/16138927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-4-16 |
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