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Knockdown of GnT-Va expression inhibits ligand-induced downregulation of the epidermal growth factor receptor and intracellular signaling by inhibiting receptor endocytosis

Changes in the expression of N-glycan branching glycosyltransferases can alter cell surface receptor functions, involving their levels of cell surface retention, rates of internalization into the endosomal compartment, and subsequent intracellular signaling. To study in detail the regulation of sign...

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Detalhes bibliográficos
Main Authors: Guo, Hua-Bei, Johnson, Heather, Randolph, Matthew, Lee, Intaek, Pierce, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667161/
https://ncbi.nlm.nih.gov/pubmed/19225046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp023
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